An oxytocin receptor in anococcygeus muscles isolated from male mice
نویسندگان
چکیده
منابع مشابه
Neuropeptide-induced contraction and relaxation of the mouse anococcygeus muscle.
Isometric tension responses to neuropeptides were recorded from anococcygeus muscles isolated from male mice. This smooth muscle tissue is innervated by inhibitory nonadrenergic, noncholinergic nerves that resemble, ultrastructurally, the peptidergic neurons of the gastrointestinal tract; the physiological function of the anococcygeus is not known. Slow sustained contractions were produced by o...
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Using a combination of reverse transcriptase polymerase chain reaction to detect specific mRNA and immunohistochemistry employing antibodies that recognize two different epitopes for each molecule, the local production of oxytocin (OT) and its cognate receptor was investigated in the male marmoset monkey (Callithrix jacchus). There was synthesis of both OT and the oxytocin receptor (OTR) within...
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The oxytocin receptor has been implicated in the regulation of reproductive physiology as well as social and emotional behaviors. The neurochemical mechanisms by which oxytocin receptor modulates social and emotional behavior remains elusive, in part because of a lack of sensitive and selective antibodies for cellular localization. To more precisely characterize oxytocin receptor-expressing neu...
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OBJECTIVES Oxytocin (OXY) in addition to peripheral actions has many central regulatory functions which can be studied on animal models. In the present study we examined in rats, which behavioral actions of OXY and long-acting carba-analog of OXY carbetocin (CBT) in the open-field can be inhibited by OXY-receptor antagonists. Our interest focused on the behavioral patterns considered indicative...
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With aging, the skeletal muscles of humans sustain decreases of approximately 30% in mass and maximum force. Contraction-induced injury may contribute to these declines. When a 225 lengthening contraction protocol (LCP) was administered to small, non-weight-bearing muscles of mice, muscles of young/adult mice recovered completely, whereas those of old mice sustained permanent deficits of 20% in...
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ژورنال
عنوان ژورنال: British Journal of Pharmacology
سال: 1986
ISSN: 0007-1188
DOI: 10.1111/j.1476-5381.1986.tb09482.x